Blood Assay Solutions

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InBlood Assay™

 

These pre-set in vitro assays are designed to offer you the possibility to get valuable data about the bioactivity of your compounds quickly. Blood Assay Solutions can design more specific assays by changing various parameters: stimulus, readout, incubation time, number of donors, negative and positive controls.

 

InBlood Assay™ – Immunoactivation

Aim: To evaluate in fresh whole blood the capacity of a compound to activate blood cells.
A cytokine release in this assay reflects the immunogenicity of the compound. This can be due to the presence of contaminants, an adjuvant-like effect, pro-inflammatory properties of the compound, a risk of cytokine release syndrome if the tested compound is a biologic.
Up to 6 donors tested on the same 96-well plate.


InBlood Assay – Immunosuppression

Aim: To evaluate in fresh whole blood the capacity of a compound to inhibit cytokine release by activated blood cells.
Biologics or small molecules can be tested in this assay which can be used as a screen for anti-inflammatory or immunosuppressive compounds.
Up to 6 donors tested on the same 96-well plate.